AZ7976 - CAS 2813866-27-0

AZ7976 (Compound 42), a potent and highly selective agonist for Relaxin Family Peptide Receptor 1 (RXFP1) with a pEC 50 value greater than 10.5, operates through an allosteric mechanism to enhance RXFP1's cAMP signaling, which physiologically elevates heart rate. This property makes AZ7976 a valuable tool in cardiovascular disease research [1].

RXFP receptor

GPCR/G Protein

2813866-27-0

C30H33F7N2O6S

682.65

N(C(=O)C1=C(OC)C=C(F)C(O[C@@H]2CC[C@@](C(O)=O)(C)CC2)=C1)[C@H]3[C@@H](C(NC4=CC(S(F)(F)(F)(F)F)=C(F)C=C4)=O)[C@]5(C[C@@]3(CC5)[H])[H]

-20°C

Ice Packs

Small Compound