Azaphilone-9 - CAS 1448460-87-4

Azaphilone-9 (AZA-9) functions as an inhibitor of the HuR-ARE RNA interaction, with an inhibition constant (IC50) of 1.2 μM, by targeting the RNA-binding protein Hu antigen R (HuR) . As HuR-RNA interactions play a critical role in stabilizing oncogenic mRNAs within tumors, Azaphilone-9 exhibits potential in inhibiting cancer cell growth and progression.

Others, HuR

Others, Chromatin/Epigenetic

1448369

C21H23BrO5

435.31

O=C1C=2C(=C(Br)C(=O)C1(OC(C)=O)C)C=C(/C=C/C(=C/[C@H](CC)C)/C)OC2

-20°C

Ice Packs

Small Compound