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Molfinity

AZD-4877 - CAS 758722-49-5

AZD-4877 - CAS 758722-49-5

MF-0063886-01

$136.31 USD
$136.31 USD
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Product Details

  • Bioactivity

    AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC) .

  • Target

    Apoptosis, Kinesin

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling

  • CAS Number

    758722-49-5

  • Purity

    0.9987

  • Molecular Formula

    C28H33N5O2S

  • Molecular Weight

    503.66

  • SMILES

    C(N(C(=O)C1=CC=C(C)C=C1)CCCN)(C(C)C)C=2N(CC3=CC=CC=C3)C(=O)C4=C(N2)SN=C4C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound