AZD-5672 - CAS 780750-65-4

AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM. AZD-5672 inhibits hERG cardiac ion channel binding and P-gp-mediated digoxin transport with IC50s of 7.3 μM and 32 μM. AZD-5672 can be used in studies about rheumatoid arthritis.

CCR, P-gp, Potassium Channel

Membrane transporter/Ion channel, Neuroscience, Microbiology/Virology, GPCR/G Protein, Immunology/Inflammation

780681

0.981

C32H38F2N2O5S2

632.78

CCN(C1CCN(CC[C@H](c2ccc(cc2)S(C)(=O)=O)c2cc(F)cc(F)c2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O

-20°C

Ice Packs

Small Compound