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AZD-6918 - CAS 905585-60-6
AZD-6918 - CAS 905585-60-6
SKU:MF-0063891-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo. AZD6918 inhibited wild-type TrkB-induced cell migration and cell growth.
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Target
Trk receptor, Others
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Related Pathways
Tyrosine Kinase/Adaptors, Others
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CAS Number
905519
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Molecular Formula
C20H20F2N6O
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Molecular Weight
398.41
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SMILES
N([C@@H](C)C1=CC=C(F)C=C1)C2=C(C#N)C=C(F)C(NC=3C=C(OC(C)C)NN3)=N2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound