AZD 7009 - CAS 335619-18-6

AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium current in isolated rabbit atrial and ventricular myocytes, and prolonged E-4031-induced action potential duration, promoting early post-depolarization of Purkinye fibers (EADs) .

Sodium Channel, Potassium Channel

Membrane transporter/Ion channel

335595

0.9851

C23H34N4O5

446.54

C([C@@H](COC1=CC=C(C#N)C=C1)O)N2CC3OC(C2)CN(CCNC(OC(C)(C)C)=O)C3

-20°C

Ice Packs

Small Compound