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AZD0233 - CAS 3036141-78-0
AZD0233 - CAS 3036141-78-0
SKU:MF-0063906-01
Regular price
$377.31 USD
Regular price
Sale price
$377.31 USD
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Product Details
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Bioactivity
AZD0233 is an orally active CX3CR1 antagonist that immunomodulates the CX3CR1/CX3CL1 signaling axis. It improves cardiac function in dilated cardiomyopathy mouse models while reducing macrophage infiltration and fibrotic scarring.
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Target
CXCR
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Related Pathways
Immunology/Inflammation, Autophagy, GPCR/G Protein
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CAS Number
3036063
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Molecular Formula
C19H29FN6O4S
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Molecular Weight
456.54
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SMILES
C([C@@H](C)C=1C(F)=CC(OC)=NC1)C=2N=C(N[C@H](CC(C)C)CO)N=C(NS(C)(=O)=O)N2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound