AZD1134 - CAS 442548-99-4

AZD1134 is an orally active, brain-penetrant, and highly selective 5-HT1B receptor antagonist with IC50 values of 2.9 nM (human) and 0.108 nM (guinea pig) . It elevates synaptic serotonin levels in guinea pigs and holds potential for research in mental disorders such as depression and anxiety.

5-HT Receptor

Neuroscience, GPCR/G Protein

442445

C28H32FN5O4

521.58

O=C1C=C(OC=2C1=CC(F)=CC2N3CCN(C)CC3)C(=O)NC4=CC=C(C=C4)N5CCN(C(=O)CC)CC5

-20°C

Ice Packs

Small Compound