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Molfinity

AZD3759 hydrochloride - CAS 1626387-81-2

AZD3759 hydrochloride - CAS 1626387-81-2

MF-0017648-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R) /EGFR (wt) /EGFR (exon 19Del) .

  • Target

    Apoptosis, EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Apoptosis

  • CAS Number

    1626304

  • Purity

    0.9962

  • Molecular Formula

    C22H24Cl2FN5O3

  • Molecular Weight

    496.36

  • SMILES

    C[C@@H]1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C.Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound