AZD4547 - CAS 1035270-39-3

AZD4547 is an FGFR family inhibitor. AZD4547 selectively inhibits FGFR1 phosphorylation and suppresses cancer cell proliferation through inhibition of FGFR1 signaling, and is able to act on FGFR1 (IC50:0.2 nM), FGFR2 (IC50:2.5 nM), FGFR3 (IC50:1.8 nM) and FGFR4 (IC50:165 nM) . IC50:165 nM) .[2]

FGFR, VEGFR

Angiogenesis, Tyrosine Kinase/Adaptors

1035228

0.9988

C26H33N5O3

463.57

COc1cc(CCc2cc(NC(=O)c3ccc(cc3)N3C[C@H](C)N[C@H](C)C3)n[nH]2)cc(OC)c1

-20°C

Ice Packs

Small Compound