AZD5718 - CAS 2041076-43-9

AZD5718 is a potent and selective FLAP inhibitor (IC50 = 2.0 nM) for Treatment of Coronary Artery Disease. AZD5718 demonstrated a dose dependent and greater than 90% suppression of leukotriene production over 24 h. Preclinical toxicology studies in rat and dog did not show any serious adverse events of clinical significance. Currently, AZD5718 is evaluated in a phase 2a study for treatment of coronary artery disease.

Others, FLAP

Immunology/Inflammation, Others

2041024

C29H34N6O4

530.62

CC=1C=C(N(N1)C2CCCCO2)C3=CC=C(C(=O)[C@H]4[C@H](C(NC5=C6N(N=C5)CCNC6=O)=O)CCCC4)C=C3

-20°C

Ice Packs

Small Compound