Azelaoyl PAF - CAS 354583-69-0

Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones with potency comparable to rosiglitazone. In atherosclerosis studies, Azelaoyl PAF promotes the uptake of oxidized low-density lipoprotein (oxLDL) by macrophages by upregulating CD36 expression. In fibroblasts from Friedreich's ataxia (FRDA) patients, Azelaoyl PAF significantly increased mRNA and protein levels of ferritin.

PPAR, Integrin

Cytoskeletal Signaling, Metabolism, DNA Damage/DNA Repair

354514

C33H66NO9P

651.85

[C@@H](COP(OCC[N+](C)(C)C)(=O)[O-])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC

-20°C

Ice Packs

Inhibitors & Agonists