Azido-PEG8-Amido-Val-Cit-PAB - CAS 2356229-77-9

Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker efficiently cleaved by cathepsin B. Since cathepsin B is localized in lysosomes, the ADC payload is released exclusively within cells. The azido group reacts with DBCO, BCN, or other alkyne groups through click chemistry. The PEG spacer enhances water solubility. Reagent grade, intended for research purposes.

ADC Linker

Antibody-drug Conjugate/ADC Related

2356229-77-9

C40H69N9O15

916.027

N(C([C@@H](NC([C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C1=CC=C(CO)C=C1

-20°C

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