Azvudine hydrochloride - CAS 1333126-31-0

Azvudine hydrochloride (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI) with strong antiviral effects against HIV, HBV, and HCV. It demonstrates highly potent inhibition of HIV-1 (EC50 ranging from 0.03 to 6.92 nM) and HIV-2 (EC50 ranging from 0.018 to 0.025 nM), and effectively inhibits NRTI-resistant viral strains.

HBV, HIV Protease, HCV Protease, Antiviral, Reverse Transcriptase

Microbiology/Virology, Proteases/Proteasome, Immunology/Inflammation

1333095

0.9906

C9H12ClFN6O4

322.68

Cl.Nc1ccn([C@@H]2O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@@H]2F)c(=O)n1

-20°C

Ice Packs

Small Compound