B-Raf IN 11 - CAS 918504-27-5

B-Raf IN 11 is a novel selective inhibitor. The DFG-in conformation of the B-Raf kinase V600E mutant is superior to the DFG-out conformation in colorectal cancer.

Raf

MAPK

918472

0.99947

C17H14BrF2N3O3S

458.28

C(=O)(C=1C=2C(NC1)=NC=C(Br)C2)C3=C(F)C(NS(CCC)(=O)=O)=CC=C3F

-20°C

Ice Packs

Small Compound