B-Raf IN 7 - CAS 2477725-07-6

B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor with an IC50 of 110.23 nM. It exhibits antitumor activity against colon carcinoma cells (HCT-116), mammary gland cells (MCF-7), hepatocellular carcinoma cells (HEPG-2), human cervical carcinoma cells (Hela), and human prostate cancer cells (PC-3), with IC50 values of 7.50, 9.87, 10.57, 11.63, and 12.83 μM, respectively [1].

Others, Raf

MAPK, Others

2477725-07-6

C15H16N6O3

328.33

NC=1N(N=NC1C(OCC)=O)C2=CC=C(C=C2)C=3CCC(=O)NN3

-20°C

Ice Packs

Small Compound