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B-Raf IN 8 - CAS 1215313-19-1
B-Raf IN 8 - CAS 1215313-19-1
SKU:MF-0137834-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC50 = 70.65 nM) with antitumor activity, demonstrating IC50 values of 9.78, 13.78, 18.52, and 29.85 μM against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7), and human prostate cancer (PC-3) cells [1].
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Target
Others, Raf
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Related Pathways
Others, MAPK
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CAS Number
1215293
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Molecular Formula
C18H17N3O2
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Molecular Weight
307.35
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SMILES
N(=CC1=CC=C(OC)C=C1)C2=CC=C(C=C2)C=3CCC(=O)NN3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound