B-Raf IN 9 - CAS 2477725-18-9

B-Raf IN 9 (compound 8b) is an effective B-Raf inhibitor (IC50=24.79 nM) that blocks the cell cycle at the G2/M phase, induces apoptosis, and exhibits potent anti-tumor activity on human prostate cancer PC-3 cells (IC50=7.83 μM) .

Raf, Apoptosis, Others

Others, Apoptosis, MAPK

2477698

C23H20N4OS

400.5

O=C1N(N=C(CC1)C2=CC=C(NC(NC3=CC=CC=C3)=S)C=C2)C4=CC=CC=C4

-20°C

Ice Packs

Small Compound