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B026 - CAS 2379416-48-3
B026 - CAS 2379416-48-3
SKU:MF-0141918-01
Regular price
$1,927.85 USD
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Sale price
$1,927.85 USD
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Product Details
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Bioactivity
B026 is a selective, orally active inhibitor of p300/CBP histone acetyltransferase (p300/CBP HAT) that acts on p300 (IC50: 1.8 nM) and CBP (IC50: 9.5 nM) . b026 exhibits anticancer effects on androgen receptor positive (AR+) prostate cancer cells.
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Target
Others, Histone Acetyltransferase
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Related Pathways
Others, Chromatin/Epigenetic
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CAS Number
2379365
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Molecular Formula
C27H23F4N5O4
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Molecular Weight
557.5
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SMILES
O=C1[C@]2(C=3C(CC2)=CC(=CC3)C4=CN(C)N=C4)NC(=O)N1CC(=O)N5[C@H](C(F)(F)F)COC=6C(C5)=CC(F)=CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound