BACE1/2-IN-1 - CAS 2671036-34-1

BACE1/2-IN-1 (compound 34) is an effective BACE1 and BACE2 inhibitor with IC50 values of 0.01 and 0.0053 μM, respectively. It exhibits a lower Pgp efflux ratio, improved passive permeability, and decreased metabolic stability in liver microsomes.

Beta Amyloid, Beta-Secretase, Others

Neuroscience, Others

2671001

C21H31N5OS

401.57

C(OC[C@H]1[C@H](C)C1)(C)(C)[C@H]2[C@]([C@@]34[C@@](CN(C3)C=5N=CC=CN5)(CSC(N)=N4)[H])(C2)[H]

-20°C

Ice Packs

Small Compound