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Bafilomycin A1 - CAS 88899-55-2

Bafilomycin A1 - CAS 88899-55-2

SKU:MF-0096039-01

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  • Bioactivity

    Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase inhibitor (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autophagosomes with lysosomes. Bafilomycin A1 also induces apoptosis.

  • Target

    Autophagy, Apoptosis, Proton pump, Antibiotic, Antibacterial

  • Related Pathways

    Microbiology/Virology, Autophagy, Membrane transporter/Ion channel, Apoptosis

  • CAS Number

    88842

  • Purity

    0.9936

  • Molecular Formula

    C35H58O9

  • Molecular Weight

    622.83

  • SMILES

    [H][C@@]1(OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C\C(C)=C\C=C\[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O)[C@H](C)[C@H](O1)C(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product