Bavarostat - CAS 2134109-20-7

Bavarostata is a highly brain penetrant HDAC6 inhibitor (IC50=60nM) . Bavarostat exhibits excellent HDAC6 selectivity (>80-fold over all other Zn-containing HDAC paralogues), modulates tubulin acetylation selectively over histone acetylation, and has excellent brain penetrance.

HDAC, Microtubule Associated, Others

Others, Chromatin/Epigenetic, DNA Damage/DNA Repair, Cytoskeletal Signaling

2134082

C20H27FN2O2

346.44

C(N(CC1=C(F)C=C(C(NO)=O)C=C1)C)C23CC4CC(C2)CC(C3)C4

-20°C

Ice Packs

Small Compound