Bavdegalutamide - CAS 2222112-77-6

Bavdegalutamide (ARV-110) is an oral protein degrader that specifically binds to AR and mediates its degradation. Bavdegalutamide can degrade clinically relevant mutant AR proteins, maintain activity in a high androgen environment, and has an acceptable safety profile.

PROTACs, Androgen Receptor

Endocrinology/Hormones, PROTAC

2222029

0.9904

C41H43ClFN9O6

812.29

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC(F)=C(C2)N4CCN(CC5CCN(CC5)C6=CC=C(C(N[C@@H]7CC[C@@H](OC8=CC(Cl)=C(C#N)C=C8)CC7)=O)N=N6)CC4

-20°C

Ice Packs

PROTAC