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BAY 11-7082 - CAS 19542-67-7
BAY 11-7082 - CAS 19542-67-7
SKU:MF-0015895-01
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$42.14 USD
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$42.14 USD
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Product Details
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Bioactivity
BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that suppresses TNFα-induced IκBα phosphorylation (IC50=10 μM) and also inhibits the ubiquitin-specific proteases USP7 and USP21 (IC50=0.19/0.96 μM) .
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Target
DUB, Autophagy, IκB/IKK, Apoptosis, NF-κB
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Related Pathways
NF-κB, Ubiquitination, DNA Damage/DNA Repair, Apoptosis, Cell Cycle/Checkpoint, Autophagy
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CAS Number
19468
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Purity
0.9992
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Molecular Formula
C10H9NO2S
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Molecular Weight
207.25
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SMILES
Cc1ccc(cc1)S(=O)(=O)\C=C\C#N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound