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BAY-155 - CAS 2163769-52-4

BAY-155 - CAS 2163769-52-4

MF-0147318-01

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Product Details

  • Bioactivity

    BAY-155 is a powerful and selective menin-MLL inhibitor, exhibiting an IC 50 of 8 nM. It significantly down-regulates MEIS1 gene expression while up-regulating CD11b and MNDA genes. BAY-155 also demonstrates anti-proliferative effects in AML/ALL (acute myeloid/lymphoblastic leukemia) models [1].

  • Target

    Epigenetic Reader Domain

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    2163769-52-4

  • Molecular Formula

    C28H28F3N7OS

  • Molecular Weight

    567.63

  • SMILES

    N#CC1=CC=2C(=CC=C(C2C)CN3CCC4(CN(C=5N=CN=C6SC(=CC65)CC(F)(F)F)C4)CC3)N1CC(=O)N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound