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Molfinity

BAY-1816032 - CAS 1891087-61-8

BAY-1816032 - CAS 1891087-61-8

SKU:MF-0004579-01

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  • Bioactivity

    BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor with IC50 of 0.7 nM and is orally active and abolishes nocodazole-induced Thr-120 phosphorylation of histone H2A, a major BUB1 target protein, in HeLa cells with IC50 of 29 nM.

  • Target

    Others, Serine/threonin kinase

  • Related Pathways

    Others, Metabolism, Cell Cycle/Checkpoint

  • CAS Number

    1891018

  • Purity

    0.9981

  • Molecular Formula

    C27H24F2N6O4

  • Molecular Weight

    534.51

  • SMILES

    COc1cnccc1Nc1nc(ncc1OC)-c1nn(Cc2c(F)cc(OCCO)cc2F)c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound