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Molfinity

BAY-218 - CAS 2162982-11-6

BAY-218 - CAS 2162982-11-6

MF-0006421-01

$35.41 USD
$22.10 USD $35.41 USD
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Product Details

  • Bioactivity

    BAY-218 is an aryl hydrocarbon receptor (AHR) antagonist with IC50 of 39.9 nM in the human glioblastoma U87 cell line. BAY-218 inhibition of AhR stimulates pro-inflammatory monocyte and T cell responses in vitro and drives anti-tumor immune responses, leading to reduced tumor growth in vivo.

  • Target

    AhR, Aryl Hydrocarbon Receptor

  • Related Pathways

    Immunology/Inflammation, Metabolism

  • CAS Number

    2162982-11-6

  • Purity

    0.9985

  • Molecular Formula

    C20H17ClFN3O3

  • Molecular Weight

    401.82

  • SMILES

    C[C@@H](CO)NC(=O)c1cc(nn(-c2cccc(F)c2)c1=O)-c1ccc(Cl)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound