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Molfinity

BAY-298 - CAS 2471978-97-7

BAY-298 - CAS 2471978-97-7

SKU:MF-0004581-01

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  • Bioactivity

    BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 96 nM, 23 nM, and 78 nM for hLH (human LH), rLH (rat LH), and cLH (cynomolgus monkey LH), respectively. It is the first nanomolar hLH-R antagonist that reduces sex hormone levels in vivo [1].

  • Target

    GNRH Receptor, Others

  • Related Pathways

    GPCR/G Protein, Others

  • CAS Number

    2471874

  • Molecular Formula

    C27H21ClFN3O2

  • Molecular Weight

    473.93

  • SMILES

    Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound