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BAY-298 - CAS 2471978-97-7
BAY-298 - CAS 2471978-97-7
SKU:MF-0004581-01
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$1,812.02 USD
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$1,812.02 USD
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Product Details
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Bioactivity
BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 96 nM, 23 nM, and 78 nM for hLH (human LH), rLH (rat LH), and cLH (cynomolgus monkey LH), respectively. It is the first nanomolar hLH-R antagonist that reduces sex hormone levels in vivo [1].
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Target
GNRH Receptor, Others
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Related Pathways
GPCR/G Protein, Others
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CAS Number
2471874
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Molecular Formula
C27H21ClFN3O2
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Molecular Weight
473.93
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SMILES
Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound