BAY-3153 - CAS 2771319-69-6

BAY-3153 is a selective CCR1 antagonist with species-specific potency values of human IC50 = 3 nM, rat IC50 = 11 nM, and mouse IC50 = 81 nM. BAY-3153 is used to investigate C-C motif chemokine receptor 1 signaling and its roles in inflammation, immune cell trafficking, and disease-associated chemokine responses.

CCR

Immunology/Inflammation, GPCR/G Protein, Microbiology/Virology

2771244

C25H29Cl2N3O4

506.42

O(CC)C=1C=C(N2C3CN(C(=O)[C@@H]4N(C[C@@H](O)C4)C5=CC=C(Cl)C=C5)CC2COC3)C=CC1Cl

-20°C

Ice Packs

Small Compound