BAY-6672 - CAS 2247517-53-7

BAY-6672 is a selective human prostaglandin F (FP) receptor antagonist that is highly potent (IC50=11 nM), orally available and well permeable. It exerts antifibrotic effects by inhibiting prostaglandin F2α (PGF2α) activity through antagonizing the FP receptor, and has in vivo efficacy in animal models of idiopathic pulmonary fibrosis (IPF) .

Prostaglandin Receptor

GPCR/G Protein, Immunology/Inflammation

2247457

0.9951

C26H27BrClN3O3

544.87

C(NC[C@H](CCC(O)=O)C1=C(Cl)C=CC=C1)(=O)C=2C3=C(N=C(C2C)N4CCCC4)C=CC(Br)=C3

-20°C

Ice Packs

Small Compound