BAY-677 - CAS 2117404-84-7

BAY-677, serving as an inactive control for BAY-678, is distinguished by BAY-678's capabilities as an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), showcasing a high potency with an IC50 of 20 nM[1]. Furthermore, BAY-678 has been publicly nominated as a chemical probe by the Structural Genomics Consortium (SGC) [2].

Others, Serine Protease

Others, Proteases/Proteasome

2117313

C20H15F3N4O2

400.35

CC(=O)C1=C(C)N(C(=O)N[C@H]1c1ccc(nc1)C#N)c1cccc(c1)C(F)(F)F

-20°C

Ice Packs

Small Compound