BAY-707 acetate - CAS 2223023-19-4

BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1. Despite superior cellular target engagement and pharmacokinetic properties, inhibition of MTH1 with BAY-707 resulted in a clear lack of in vitro or in vivo anticancer efficacy either in mono- or in combination therapies.

Others, DNA/RNA Synthesis

Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair

2223000

C17H24N4O4

348.18

CC(O)=O.CCNC(=O)c1cc2c(ccnc2[nH]1)N1CCOC[C@@H]1C

-20°C

Ice Packs

Small Compound