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Bayer-18 - CAS 1251752-12-1
Bayer-18 - CAS 1251752-12-1
SKU:MF-0142606-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
Bayer-18 is an inhibitor of TYK2. It inhibits the viability of anaplastic large cell lymphoma cells, including K299, SR786, Mac1, and Mac2a, with an IC50 ranging from 2-3 μM. Additionally, Bayer-18 induces apoptosis in K299 and SR786 cells.
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Target
Apoptosis, JAK
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Related Pathways
Stem Cells, Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Apoptosis
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CAS Number
1251739
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Molecular Formula
C19H27FN6O2
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Molecular Weight
390.46
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SMILES
O=C(NC1=CC=CC(=C1)NC2=NC=C(F)C(=N2)NC(C)(C)CO)NC(C)(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound