BChE/HDAC6-IN-1 - CAS 2925457-27-6

BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor exhibiting potent and selective inhibition with IC50 values of 4 nM for BChE and 8.9 nM for HDAC6. It demonstrates efficacy in alleviating cognitive deficits in an Aβ1–42-induced mouse model, indicating its potential utility in Alzheimer's disease research [1].

HDAC, Cholinesterase (ChE)

DNA Damage/DNA Repair, Chromatin/Epigenetic, Neuroscience

2925424

C34H43N5O5

601.74

C(N(CC)CC)C1=C(CNC(=O)C2=CC(NC(=O)C3=CC(NC(CCCCCCC(NO)=O)=O)=CC=C3)=CC=C2)C=CC=C1

-20°C

Ice Packs

Small Compound