BChE-IN-20 - CAS 1428439-79-5

BChE-IN-20 (compound 7c) is a potent and selective inhibitor of BChE, with IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE. It also inhibits P glycoprotein with an IC50 of 0.27 μM. BChE-IN-20 serves as a promising template for the design and development of pharmaceutical BChE-selective ligands, including inhibitors and fluorogenic probes.

Cholinesterase (ChE), Others

Neuroscience, Others

1428439-79-5

C27H39N5O2

465.63

O=C(OC)C1=CN(CCC=2N=C(N=C(NCCCN(CC)CC)C2C1)C=3C=CC=CC3)C(C)C

-20°C

Ice Packs

Small Compound