BChE-IN-8 - CAS 2653349-78-9

BChE-IN-8 (compound 20) is an orally active butyrylcholinesterase (BChE) inhibitor that crosses the blood-brain barrier, targeting eqBChE (IC50: 0.15 nM) and hBChE (IC50: 45.2 nM) . It is used in Alzheimer's disease (AD) research for its neuroprotective and cognitive improvement effects, affecting the cholinergic system, Aβ aggregation, and neuropeptide levels.

Beta Amyloid, Others

Neuroscience, Others

2653262

C18H12BrN7O2

438.24

C(C(NC1=CC(C#N)=CC(Br)=C1)=O)N2C(=NC=3C2=CC=CC3)C=4C(N)=NON4

-20°C

Ice Packs

Small Compound