BCL-xL/BCL-2 ligand 1 - CAS 2941091-91-2

Compound 72-1, also known as BCL-xL/BCL-2 ligand 1, serves as a ligand for BCL-xL and BCL-2 proteins. It can be tethered to an E3 ligase via a linker, facilitating the formation of PROTACs [1] [2].

Ligand for E3 Ligase

PROTAC

2941091-91-2

C48H53ClF3N5O7S3

1000.61

C(C1=C(CC[C@](C=O)(C)C1)C2=CC=C(Cl)C=C2)N3CCN(CC3)C4=CC=C(C(NS(=O)(=O)C5=CC(S(C(F)(F)F)(=O)=O)=C(N[C@H](CCN6[C@@]7(C[C@](C6)(OC7)[H])[H])CSC8=CC=CC=C8)C=C5)=O)C=C4

-20°C

Ice Packs

PROTAC