BCL6 PROTAC 1 - CAS 2257479-54-0

BCL6 PROTAC 1 is a selective B-cell lymphoma 6 (BCL6) proteolysis targeting chimera (PROTAC) that inhibits the BCL6 cell reporter with an IC50 of 8.8 μM and significantly degrades BCL6 in diffuse large B-cell lymphoma (DLBCL) cell lines, making it valuable for tumor-related research [1].

Others, PROTACs, Bcl-6

Immunology/Inflammation, Others, PROTAC

2257425

C45H52ClN9O12

946.4

[H][C@]12CN(CCN1c1ncc(Cl)c(Nc3cc4CCC(=O)N(C)c4c(OCCOC2)c3)n1)C(=O)CCC(=O)NCCCOCCOCCOc1cccc2C(=O)N([C@H]3CCC(=O)NC3=O)C(=O)c12

-20°C

Ice Packs

PROTAC