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BCR-ABL-IN-5 - CAS 1795736-60-5

BCR-ABL-IN-5 - CAS 1795736-60-5

MF-0050982-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    BCR-ABL-IN-5 is a Bcr-Abl (Breakpoint cluster region-Abelson) kinase inhibitor that acts on Bcr-AblWT (IC50: 0.014 μM) and Bcr-AblT3151 (IC50: 0.45 μM) and exhibits some anti-proliferative effects on leukemic cells. effect.

  • Target

    Others, Bcr-Abl

  • Related Pathways

    Others, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    1795671

  • Molecular Formula

    C25H21Cl2N5O2

  • Molecular Weight

    494.37

  • SMILES

    NC=1C2=C(C=CC=C2NN1)C3=CC=C(C(=O)N4CCN(C(=O)C5=C(Cl)C=C(Cl)C=C5)CC4)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound