BCR-ABL-IN-6 - CAS 2499499-26-0

BCR-ABL-IN-6 (9h) is an imatinib derivative and a selective inhibitor of Bcr-Abl kinase, showing activity on Bcr-AblWT (IC50: 4.6 nM) and Bcr-AblT3151 (IC50: 277 nM) . BCR-ABL-IN-6 (9h) is utilized in studying chronic myeloid leukemia treatment.

Others, Bcr-Abl

Others, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

2499473

C27H22F3N5O2

505.49

C(F)(F)(F)C1=C(C=CC(C(NC2=CC(C#CC3=C4C(NN=C4N)=CC=C3)=CC=C2)=O)=C1)N5CCOCC5

-20°C

Ice Packs

Small Compound