BCRP-IN-2 - CAS 2953730-35-1

BCRP-IN-2 is a compound with BCRP inhibitory activity, exhibiting enhanced inhibition of BCRP upon UV activation. It serves as a valuable probe for studying interactions between quinazoline amine derivatives and BCRP, and it stimulates ATP hydrolysis of the BCRP transporter, leading to increased mitoxantrone accumulation in BCRP-overexpressing H460/MX20 cells.

BCRP

Membrane transporter/Ion channel

2953694

C19H13N7

339.35

[N-]=[N+]=NC1=CC=C(C=C1)NC2=NC(=NC3=CC=CC=C32)C=4C=CN=CC4

-20°C

Ice Packs

Small Compound