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BDA-366 - CAS 1909226-00-1

BDA-366 - CAS 1909226-00-1

MF-0096884-01

$45.13 USD
$45.13 USD
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Product Details

  • Bioactivity

    BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-apoptotic entity. This compound effectively suppresses lung cancer cell growth[1].

  • Target

    Bcl-2 Family

  • Related Pathways

    Apoptosis

  • CAS Number

    1909226-00-1

  • Purity

    0.9946

  • Molecular Formula

    C24H29N3O4

  • Molecular Weight

    423.5

  • SMILES

    N(C[C@H]1CO1)C2=C3C(=C(NC[C@@H](CN(CC)CC)O)C=C2)C(=O)C=4C(C3=O)=CC=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound