BDS-I - CAS 207621-38-3

BDS-I, a marine toxin derived from Anemonia sulcata, functions as a selective inhibitor of the potassium channel, specifically targeting Kv3.4. It impedes the Aβ1-42-induced augmentation of Kv3.4 activity, caspase-3 activation, and distortion of nuclear morphology in NGF-differentiated PC-12 cells. Moreover, BDS-I effectively counteracts the cell death induced by the Aβ peptide [1].

Potassium Channel

Membrane transporter/Ion channel

207580

C210H297N57O56S6

4708.34

-20°C

Ice Packs

Peptide