BDW568 - CAS 335401-44-0

BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist. This compound effectively induces STING transcriptional activity, evidenced by a reporter assay in THP-1 cells, with an EC50 value of 7.6 μM. Furthermore, at a concentration of 50 μM, BDW568 prompts phosphorylation of TANK-binding kinase 1 (TBK1) and IFN regulatory factor 3 (IRF3) within THP-1 cells, showcasing its biochemical activity in cellular signaling pathways.

Others, STING

Others, Immunology/Inflammation

335401-44-0

C12H12N4O2S2

308.38

O=C(OC)CSC1=NN=C2N1C=NC3=C2C(C)=C(C)S3

-20°C

Ice Packs

Small Compound