Beauveriolide I - CAS 154491-55-1

Beauveriolide I is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 μM, as well as inhibits cholesterol synthesis (IC50= 0.78 μM), in primary mouse peritoneal macrophages.1,2Beauveriolide I also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 6 μM) .2

Others, Endogenous Metabolite

Others, Metabolism

154435

C27H41N3O5

487.63

[H][C@]1(CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@]([H])(CC(C)C)C(=O)O1)[C@@H](C)CCCC

-20°C

Ice Packs

Natural Product