Beauverolide Ja - CAS 76265-41-3

Beauverolide Ja, a cyclotetradepsipeptide and secondary metabolite of Isaria fumosorosea [1], functions as a potent inhibitor of calmodulin (CaM), exhibiting a dissociation constant (Kd) of 0.078 μM and an inhibition constant (Ki) of 0.39 μM for Ca2+-CaM.

CaMK, Endogenous Metabolite, Others

Neuroscience, Others, Metabolism

76221

C35H46N4O5

602.76

[H][C@@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CC(OC1=O)C(C)CCCC)[C@@H](C)CC

-20°C

Ice Packs

Natural Product