Beclometasone dipropionate - CAS 5534-09-8

Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.

ROS, Glucocorticoid Receptor, Reactive Oxygen Species, NO Synthase

Metabolism, Immunology/Inflammation, Endocrinology/Hormones, NF-κB

5534-09-8

0.9944

C28H37ClO7

521.04

[H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)C1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

-20°C

Ice Packs

Small Compound