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Beclomethasone 17-propionate - CAS 5534-18-9

Beclomethasone 17-propionate - CAS 5534-18-9

SKU:MF-0004614-01

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  • Bioactivity

    Beclomethasone 17-propionate is a glucocorticoid that is the active metabolite of Beclomethasone dipropionate (BDP) . As a glucocorticoid receptor (GR) agonist, 17-BMP has a 13-fold higher affinity than BDP and inhibits the production of pro-inflammatory cytokines, such as CXCL8, TNF-α, and IL-6, thus exerting an anti-inflammatory effect, and it is mainly used in the treatment of asthma and allergic rhinitis.

  • Target

    Drug Metabolite, Glucocorticoid Receptor

  • Related Pathways

    Endocrinology/Hormones, Metabolism

  • CAS Number

    5534-18-9

  • Purity

    0.9806

  • Molecular Formula

    C25H33ClO6

  • Molecular Weight

    464.98

  • SMILES

    O(C(CC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](Cl)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound