Begacestat - CAS 769169-27-9

Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor (γ-secretase) that inhibits Amyloid-beta production with nanomolar potency, selectively inhibits cleavage of APP in cellular level Notch cleavage assays, reverses situational memory deficits, and can be used to study Alzheimer's disease.

Gamma-secretase, Beta Amyloid

Proteases/Proteasome, Stem Cells, Neuroscience

769133

C9H8ClF6NO3S2

391.74

C([C@H](NS(=O)(=O)C=1SC(Cl)=CC1)CO)(C(F)(F)F)C(F)(F)F

-20°C

Ice Packs

Small Compound