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Benastatin A - CAS 138968-85-1

Benastatin A - CAS 138968-85-1

SKU:MF-0152396

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  • Bioactivity

    Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 μM for the rat liver enzyme) .2Benastatin A is active against several bacteria, including methicillin-resistantS. aureus (MRSA; MIC = 3.12 μg/ml) . It induces apoptosis and cell cycle arrest at the G1/G0phase in Colon 26 mouse colon cancer cells when used at concentrations of 20 and 16 μM, respectively.3

  • Target

    Others, GST

  • Related Pathways

    Oxidation-Reduction, Others

  • CAS Number

    138882

  • Molecular Formula

    C30H28O7

  • Molecular Weight

    500.54

  • SMILES

    CCCCCc1cc2ccc3c(O)c4C(=O)c5c(O)cc(O)cc5C(C)(C)c4cc3c2c(O)c1C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound